In the title compound, C27H18Cl2N 2O2, the 2-chloroquinoline and 6-chloroquinoline rings are almost planar, with maximum deviations from their mean planes of 0.072 (1) and 0.044 (1) Å, respectively, for the Cl atoms. The inter-planar angle between these rings is 14.36 (5)°. The inter-planar angle between the 6-chloroquinoline and phenyl rings is 66.00 (8)°. In the crystal, molecules are inter-linked by weak C-H⋯O, C-H⋯π and π-π stacking [centroid-centroid distances = 3.7453 (10) and 3.7557 (9) Å] inter-actions.

Mohana Roopan S

Department of Chemistry

School of Advanced Sciences

Vellore Campus

Kumar R

Computer Science

School of Computer Science and Engineering

Chennai Campus

Nawaz Khan F

Hathwar V.R

Akkurt M.

Fulltext

Vellore Institute of Technology (VIT) is a private university located in&nbsp;Tamil Nadu, India. Founded in 1984, as Vellore Engineering College, the institution offers 20 undergraduate, 34 postgraduate, four integrated and four research programs. It has campuses in Vellore, Amravati, Bhopal and Chennai.

VIT is one of the top ranked private universities in India according to NIRF, THE and QS Rankings.&nbsp;Govt. of India has recognized&nbsp;VIT, Vellore as an&nbsp;Institution of Eminence. This has allowed VIT to take independent quality initiatives and move up in world ranking.

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VIT University

1-{6-Chloro-2-[(2-chloro-3-quinol-yl)meth-oxy]-4-phenyl-3-quinol-yl}ethan-1-one.

Acta Crystallographica Section E Structure Reports Online

In the title compound, C28H20Cl2N 2O2, the 2-chloroquinoline and 6-chloroquinoline ring systems are twisted slightly, making a dihedral angle of 4.05 (3)°. The dihedral angle between the 2quinoline ring system and the phenyl ring attached to it is 74.43 (5)°. In the crystal structure, a pair of inter-molecular C-H⋯O hydrogen bonds connect the molecules, forming centrosymmetric dimers with R22(16) motifs. The dimers are further consolidated by a C-H⋯π inter-action and a π-π stacking inter-action with a centroid-centroid distance of 3.6562 (10) Å.

1-{6-Chloro-2-[(2-chloro-6-methylquinolin-3-yl)methoxy]-4-phenylquinolin-3-yl}ethanone

In the title compound, C30H24Cl2N 2O3, the two quinoline ring systems are almost planar [maximum deviations = 0.029 (2) and 0.018 (3) Å] and the dihedral angle between them is 4.17 (8)°. The dihedral angle between the phenyl ring and its attached quinoline ring is 69.06 (13)°. The packing is stabilized by C - H⋯O, C - H⋯N, weak π-π stacking [centroid-centroid distances = 3.7985 (16) and 3.7662 (17) Å] and C - H⋯π inter-actions.

Ethyl 6-chloro-2-[(2-chloro-7,8-dimethylquinolin-3-yl)methoxy]-4-phenylquinoline-3-carboxylate

Medicinal Chemistry Research

Design and synthesis of 2-quinolones as antioxidants and antimicrobials: a rational approach

Journal of Medicinal Chemistry

3-Aryl-2-Quinolone Derivatives: Synthesis and Characterization of In Vitro and In Vivo Antitumor Effects with Emphasis on a New Therapeutical Target Connected with Cell Migration

Journal	Acta Crystallographica Section E Structure Reports Online
Publisher	International Union of Crystallography (IUCr)
ISSN	16005368
Open Access	Yes