This paper reports the wear characteristics of the ceramic coatings made with Al2O3 and also with SiC which were performed using atmospheric plasma spraying technique on the Ti-6Al-4V biomedical alloy with the aim of improving their tribological behavior. The wear behavior of the coatings was evaluated using reciprocatory wear tester with coated substrate as the flat and alumina ball as a friction partner in simulated body fluid (Hank's solution) environment. The microstructure and phase composition of the ceramic powders and as-sprayed coatings have been characterized using scanning electron microscope and X-ray diffractometer. Porosity, microhardness, adhesion strength and roughness of the coatings were measured as they have a bearing on wear and friction behavior. The results indicate that plasma sprayed Al2O 3 coating exhibits higher wear resistance compared to that of plasma sprayed SiC coating. The higher wear resistance of Al2O3 coating is attributed to the improved melting and spreading of the alumina particles onto the substrate yielding increasingly bonded splats, resulting in compact and dense microstructure with lower porosity and higher microhardness. © 2013 Indian Institute of Metals.