Applications of computer and information technology are indispensable in various fields especially in the field of biology. The use of computer aided tools plays a key role in solving biological problems. The spontaneous process of molecular docking is important for finding potentially strong candidate of drug for various viruses. The binding of protein receptors with ligand molecules is essential in drug discovery process. The aim of molecular docking tools is to predict the interaction between protein and ligand. This review outlines the major tools for protein - ligand docking which in turn emphasize the importance of molecular docking in modern drug discovery process.

Kannadasan R

Department of Software Systems

School of Computer Science and Engineering

Vellore Campus

Arnold Emerson I

Department of Biotechnology

School of Bio Sciences and Technology

Saleembasha M.S

Vellore Institute of Technology (VIT) is a private university located in&nbsp;Tamil Nadu, India. Founded in 1984, as Vellore Engineering College, the institution offers 20 undergraduate, 34 postgraduate, four integrated and four research programs. It has campuses in Vellore, Amravati, Bhopal and Chennai.

VIT is one of the top ranked private universities in India according to NIRF, THE and QS Rankings.&nbsp;Govt. of India has recognized&nbsp;VIT, Vellore as an&nbsp;Institution of Eminence. This has allowed VIT to take independent quality initiatives and move up in world ranking.

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VIT University

International Journal of Engineering Research in Africa

Context aware applications are seeking for the technologies that provides regularly available data between internal and external environments. Wireless access infrastructure is integrating real time data and heterogeneous devices to establish ubiquitous communication. A wireless sensor network (WSN) is primarily undertaking remote monitoring of any task in any sensing field further to extend for context fetching and refining to collect essential context information for pervasive environment. The applications are well utilized on context observation and interpretation for mobile users. The proposed method assists to combine various basic low level contexts to provide reliable decision making in the pervasive environment using sensor networks and context aware computing. Pervasive computing has powerful and influencing factors to establish dynamic and smart environment with its dominant features in the backend. Pervasiveness provides the regulated smart interactions and interfaces together to avail the information for various applications. Using rich context for event notification than simple position and time, aim to bring automated decision along with accuracy information. The proposed model also facilitate users and group members to create and submit an event. It provides ability to submit an event using a various mode of input. © 2018 The Authors. Published by Elsevier Ltd.

Fulltext

Procedia Computer Science

Contexts enabled Decision Making using sensors to perceive pervasive environment

Cloud is referred to as a collection of infrastructure services, such as Infrastructure as a service (IaaS) and Platform as a service (PaaS), which are made available to us for utilization by various organizations in which the key factor is virtualization of data as it allow the user to manage, handle and compute a large number of tasks very easily. By referring to Cloud technologies we mean runtime such as Hadoop, Dryad and other Map Reduce frameworks. In this paper we would analyse the above mentioned software's and techniques for the cloud system by comparing them on the basis of its processing speed, its data handling capacity, the nature of user friendliness. We would discuss large scale data analysis using different implementations on the above mentioned tools and after that we would give a performance analysis of these tools on the given implementation like Cap3, HEP, Cloudburst. © 2018 The Authors. Published by Elsevier Ltd.

High Performance Parallel Computing with Cloud Technologies

Wireless sensor network being a dominant prerequisite in the modern pervasive environment has nodes connected with multi-hop to transmit and reinforce continuous monitoring with real-time updates from the field environment. To achieve pervasiveness integrating wireless and physical devices is unavoidable. Numerous self-organized tiny sensor nodes cooperate with each other to form the clusters and the most prominent node act as cluster head (CH). The cluster head pioneered based on its battery forte whose failure affects rest of the communications. In this paper, we discuss on the essential of idle resource sharing using participatory devices as relay nodes along with node failure rate and node density to achieve reliable communication. The earlier performances are observed and results are revealed. Hence we concentrate on minimizing the task of CH using relay nodes such as participatory devices and the faulty nodes are identified over Poisson distribution which observes the failure probability without affecting communication and reduced resource consumption. © 2016, Springer-Verlag Berlin Heidelberg.

Microsystem Technologies

Sustainable life-span of WSN nodes using participatory devices in pervasive environment

Carbohydrate Polymers

Spectral investigation and characterization of host–guest inclusion complex of 4,4′-methylene-bis(2-chloroaniline) with beta-cyclodextrin

Applied Mechanics and Materials

Fungicides Inhibition Analysis by Molecular Docking and Sensitivity Testing of Penicillium italicum

Journal of Molecular Recognition

Latest developments in molecular docking: 2010-2011 in review

Advanced Materials Research

Functional Study of AcoX, an Unknown Protein Involved in Acetoin Catabolism

A Frame Work for Learning Drug Designing through Molecular Modelling Software Techniques and Biological Databases for Protein-Ligand Interactions

Journal	International Journal of Engineering Research in Africa
Publisher	Trans Tech Publications, Ltd.
Open Access	0