The vending machine is an example of a real time system. There are many vending machines available for public like coffee vending machine, ice cream vending machine, chocolates vending machine and coin vending machine. The use of vending machine for health domain needs a comprehensive study. The pharmacy department of any hospital or clinic needs the transactions to be quick and simplified. In this paper we investigate how to design a vending machine for tablets and medicines. The pills remainder with smart alarm system can be recommended for adult persons who forget to take medicines in time. The enough number of vending machines can be kept in the hospitals or road highways, airports for quick and easy access to tablet and medicine transactions. One of the challenging tasks of ongoing project of smart city is to minimize the number of accidents in the road traffic and install the first aid boxes in regular intervals of highways for easy access of medicines. This can be done by the design of smart vending machines with low budget which can be installed on the roadsides for easy access to everyone. The purpose of this vending machine is to sell the tablets or pills automatically to the patients or needy persons. The payment of this can be by insertion of coins or rupee notes to the machine. This machine has a user friendly interface which displays the menu of basic emergency available tablets or medicines like headache, cold, fever, cottons and bandage, etc. Here we study the design and development process and simulate a program for automatic pill vending machine. © 2016, International Journal of Pharmacy and Technology. All rights reserved.