This article is primarily focusing on the existence of Sobolev-type Hilfer fractional neutral integro-differential systems via measure of noncompactness. We study our primary outcomes by employing fractional calculus, measure of noncompactness and fixed point technique. First, we discuss the existence of mild solution for the fractional evolution system. Then, we extend our results to discuss the system with nonlocal conditions. Finally, we provide theoretical and practical applications to illustrate the obtained theory. © 2020 Wiley Periodicals LLC