This paper depicts simple and a helpful conclusion (normal or abnormal) of iris disease utilizing Wavelet Transform. The factual parameter like entropy extend are processed for iris image procured by Wavelet Transform and Wavelet Packet Transform. These parameters decide the variations from the norm showed in the iris image.In Image processing, we are introducing a novel approach to Wavelet transformation with respect to statistical parameter which are used to identify the tumor. The aim of this paper is to analyze this biomedical signal from the biomedical image of iris cancer and gather the information to diagnose, monitor, therapy control and evaluation. © RJPT All right reserved.