Over few decades, the Transmission Control Protocol (TCP) has been employed for developing the major Internet applications. Eventhough of which TCP has some major challenging issues when it operates in the Wireless Networks (WN). Some of the issues are identified from the existing techniques which are Packet Dropping Rate (PDR) and Packet Reception Time (PRT). The identified issues are mainly used to estimate the end-to-end performance of TCP which reveals poor result for existing TCP-Variants of TCP-Newreno which is found by the proposed technique of TCP-EPRT. TCP-EPRT is revealed the following results for its most estimable achievement when the existing and proposing techniques were comparatively analyzed. With the technique of Explicit Loss Notification (ELN), we were achieved higher throughput as compared to TCP-Newreno. The proposed work is thoroughly evaluated by Network Simulator Tool (Version NS2.34). The resultant of TCP-EPRT and TCP-Newreno shown that the PDR of TCP-EPRT is .38% and PDR of TCP-Newreno is .53%, the PRT of TCP-EPRT three-fourth time better than PRT of TCP-Newreno, the throughput of TCP-EPRT is 99.3% which is most effective than the throughput of TCP-Newreno which is 97.1% over Wireless Networks. © IDOSI Publications, 2012.