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A Numerical Representation Method for a DNA Sequence Using Gray Code Method
Published in Springer Singapore
Volume: 1057
Pages: 645 - 654
The exceptional speed in increase of genomic data at public databases requires advanced computational tools to perform quick gene analysis. The tools can be devised with the aid of genomic signal processing. The pivotal task in genomic signal processing is numerical mapping. In numerical mapping, the string of nucleotides is transformed into discrete numerical sequence by assigning optimum mathematical descriptor to a nucleotide. The descriptor must be compatible with the further stages of genomic application in order to achieve high efficiency. In this work, a simple numerical mapping method is proposed in which the optimum descriptor value is obtained by applying Gray code concept. The proposed method is evaluated on benchmark databases HRM195 and ASP67 for an identification of protein coding region application. The proposed method exhibits improved exon prediction efficiency in terms of performance accuracy and equal error rate when compared with similar methods. © 2020, Springer Nature Singapore Pte Ltd.
About the journal
JournalData powered by TypesetAdvances in Intelligent Systems and Computing Soft Computing for Problem Solving
PublisherData powered by TypesetSpringer Singapore
Open Access0