Reclaimed Asphalt Pavement (RAP) is a widely used recycled material in pavement construction. Whereas the integration of RAP into asphalt mixtures is a complex subject and need to understand every aspect that entailed in the mix design. The aim of this review paper is to provide comprehensive knowledge about the developments and challenges of the RAP in the asphalt mixtures, along with the mechanisms involved. The blending process and rejuvenator are two key factors that govern RAP content, and this can even surge up to 100% in the asphalt mixtures. The blending between the RAP and the virgin materials is very crucial in the context of performance and durability of RAP mixtures. While rejuvenator is an additive which may act as a catalyst and enhance the aged RAP binder properties. A detailed description of distinct types of the rejuvenators and their performances are discussed in this paper. Several aspects of the RAP mixtures including mix design, constituent materials, performance, RAP with polymer modified asphalt binder, as well as environmental benefits are highlighted. This study gives information to the researchers, engineers, and designers about the RAP technology. © 2019, Higher Education Press Limited Company.