A straight-forward and practical metal-free amidation and transesterification of esters have been exemplified in this protocol. This strategic reaction features mild bases and devoid of additives at a reasonable temperature (55 °C). The wide range of amines including aromatic amines, was successfully subjected to amidation that supplements the scope exploration. Likewise, various transesterification products from alcohols were realized under this optimized condition.

Thirumanavelan G

Department of Chemistry

School of Advanced Sciences

Vellore Campus

Shanmugam Karthik

Ramdas Sreedharan

Vellore Institute of Technology (VIT) is a private university located in&nbsp;Tamil Nadu, India. Founded in 1984, as Vellore Engineering College, the institution offers 20 undergraduate, 34 postgraduate, four integrated and four research programs. It has campuses in Vellore, Amravati, Bhopal and Chennai.

VIT is one of the top ranked private universities in India according to NIRF, THE and QS Rankings.&nbsp;Govt. of India has recognized&nbsp;VIT, Vellore as an&nbsp;Institution of Eminence. This has allowed VIT to take independent quality initiatives and move up in world ranking.

&nbsp;

&nbsp;

VIT University

ChemistrySelect

Nature Communications

Highly selective transition-metal-free transamidation of amides and amidation of esters at room temperature

Angewandte Chemie International Edition

Cross-Coupling of Alkyl Redox-Active Esters with Benzophenone Imines: Tandem Photoredox and Copper Catalysis

Accounts of Chemical Research

Decarbonylative Cross-Couplings: Nickel Catalyzed Functional Group Interconversion Strategies for the Construction of Complex Organic Molecules

Chemistry - A European Journal

Fluoride-Catalyzed Esterification of Amides

Nature Catalysis

Decarboxylative C(sp3)–N cross-coupling via synergetic photoredox and copper catalysis

A Straightforward Metal-Free and Mild Base Promoted Amidation and Transesterification via Acyl C-O bond Cleavage-An Expedite Synthesis of Aromatic Amides and Esters

Journal	Data powered by TypesetChemistrySelect
Publisher	Data powered by TypesetWiley
ISSN	2365-6549
Open Access	0