Background: Asthma, a major problem facing our polluted environment. It is a reversible and curable disease. Symptoms of asthma include episodic breathlessness or dyspnoea (especially at night or early morning, or after some exertion),Wheezing, Cough (especially at night or early morning, or after some exertion) and Chest tightness. Treatment of asthma includes the class of drugs from beta-blockers (Salbutamol, formoterol) and inhaled corticosteroids (beclomethasone, budesonide).Majorly compared with the oral and I.V’s, Inhalation route has more efficacy. Aim: A detailed study of inhalation drugs and its socio-economic benefits to asthma in the northern parts of Tamilnadu. Methods: A multicenter, noncomparative,random sampling study was conducted in five hundred asthmatic patients in northern parts of Tamilnadu (includes Chennai and suburb districts).Based on treatment patients were grouped as inhalation and oral medication. Inhalation shows more efficacy in the treatment of asthma. currently, inhalation drugs are classified into relievers and controllers. The drugs are administered through inhalation route via. Dry powder inhaler and Pressurized metered dose inhaler. Results: A total of 500 asthmatic patients were surveyed in this study. the inhalation drugs were administered through inhalers like DPI, pMDI and nebulizers with 47%, 50% and 3% patients adhered respectively. a combination of Reliever and controller (ICS+LABA) shows significant control in asthma management than other monotherapy. Two hundred seventy-one asthma patients experienced less exacerbation after medication. Conclusion: In asthma management, All the inhalation drugs in combination show better control and superior patients response in the management of asthma with more impact on economic aspects of the patients.