Education institutions like Schools, colleges, and universities in India are currently based on traditional learning methods and follow the conventional setting of face-to-face interaction/lectures in a classroom. Most of the academic sector started unified learning, still most of them struct with old steps. The unexpected Plague of a deadly infection called COVID-19 caused by (SARS-Cov-2) trembled the whole world. The WHO announced it as a disease outbreak. This circumstance challenged the whole education system worldwide and compelled educators to change to an online mode immediately. Many educational organizations that were earlier unwilling to change their traditional didactic practice had no choice but to move exclusively to online teaching–learning. This article provides an elaborate discussion about the education sector's impact during a disease outbreak in India. It offers a detailed discussion regarding how India adopts the e-learning approach in this critical situation. Further, it describes how to cope with the challenges related to e-learning. © 2021, The Society for Reliability Engineering, Quality and Operations Management (SREQOM), India and The Division of Operation and Maintenance, Lulea University of Technology, Sweden.