Rajendran P

Department of Mathematics

School of Advanced Sciences

Vellore Campus

Sen S.

Vellore Institute of Technology (VIT) is a private university located in&nbsp;Tamil Nadu, India. Founded in 1984, as Vellore Engineering College, the institution offers 20 undergraduate, 34 postgraduate, four integrated and four research programs. It has campuses in Vellore, Amravati, Bhopal and Chennai.

VIT is one of the top ranked private universities in India according to NIRF, THE and QS Rankings.&nbsp;Govt. of India has recognized&nbsp;VIT, Vellore as an&nbsp;Institution of Eminence. This has allowed VIT to take independent quality initiatives and move up in world ranking.

&nbsp;

&nbsp;

VIT University

Environmental Nanotechnology, Monitoring & Management

Nanotechnology for Environmental Engineering

Adsorption studies of carbamazepine by green-synthesized magnetic nanosorbents

Metal nanoparticles have a great impact and even change the composition of soil microbial communities. This poses the risk of their accumulation in the ecosystem, which may call on health hazard. Statistical techniques such as Plackett-Burman design, Response Surface Methodology were used for optimizing medium constituents for Bacillus cereus SVK1 and other critical variables responsible for the production of biomolecules and biosynthesis of hematite nanoparticles. The effect of hematite nanoparticles on the growth of soil bacteria were tested by agar-well diffusion method and dynamic growth curve techniques. Bacterial growth inhibition was not observed with hematite nanoparticle concentration of up to 25mg/mL. In addition, hematite nanoparticles enhanced the growth of the soil bacteria. The results show that hematite nanoparticles were non-toxic to soil bacteria indicating their scope for wide range of applications. The effective cytotoxic concentration (CTC50) of hematite nanoparticles against MCF-7, A549, Hep3B and Vero cell lines was found to be 207.58, 224.69, 193.26 and 2530μg/mL respectively. Hematite nanoparticles didn't cause lysis of red blood cells.

Colloids and Surfaces B: Biointerfaces

Evaluation of cytotoxicity of hematite nanoparticles in bacteria and human cell lines

Hematite (α-Fe2O3) nanoparticles are widely used in various applications including gas sensors, pigments owing to its low cost, environmental friendliness, non-toxicity and high resistance to corrosion. These nanoparticles were generally synthesized by different chemical methods. In the present study, nanoparticles were synthesized rapidly without heat treatment by biosynthesis approach using culture supernatant of Bacillus cereus SVK1. The physiochemical parameters for rapid synthesis were optimized by using UV-visible spectroscopy. The time taken for hematite nanoparticle synthesis was found to increase with the increasing concentration of the precursor. This might be due to the inadequate proportion of quantity of biomolecules present in the culture supernatant to the precursor which led to delayed bioreduction. Greater quantities of culture supernatant with respect to precursor lead to rapid synthesis of hematite nanoparticles. The nucleation of the hematite nucleus happens more easily when the solution pH was less than 10. The optimum parameters identified for the rapid biosynthesis of hematite nanoparticles were pH9, 37°C (temperature) and 1mM ferric chloride as precursor. The particles were well crystallized hexagonal structured hematite nanoparticles and are predominantly (110)-oriented. The synthesized nanoparticles were found to contain predominantly iron (73.47%) and oxygen (22.58%) as evidenced by Energy Dispersive X-ray analysis. Hematite nanoparticles of 15-40nm diameters were biosynthesized in 48h under optimized conditions, compared to 21days before optimization.

Journal of Photochemistry and Photobiology B: Biology

Optimization of process parameters for the rapid biosynthesis of hematite nanoparticles

Iron oxide nanoparticles were gaining significant importance in a variety of applications due to its paramagnetic properties and biocompatibility. Various chemical methods were employed for hematite nanoparticle synthesis which require special equipment or a complex production process. In this study, protein capped crystalline hexagonal hematite (α-Fe2O3) nanoparticles were synthesized by green approach using culture supernatant of a newly isolated bacterium, Bacillus cereus SVK1 at ambient conditions. The synthesized nanoparticles were characterized by electron microscopy, X-ray diffraction, UV-visible spectroscopy and Fourier transform infrared spectroscopic analysis. Nanoparticles were evaluated for its possible anticancer activity against HepG2 liver cancer cells by MTT assay. Hematite nanoparticles with an average diameter of 30.2 nm, exhibited a significant cytotoxicity toward HepG2 cells in a concentration-dependent manner (CTC50=704 ng/ml).

International Journal of Biological Macromolecules

Biosynthesis of hematite nanoparticles and its cytotoxic effect on HepG2 cancer cells

Environmental Engineering and Management Journal

REMOVAL OF CARBAMAZEPINE BY ELECTROCOAGULATION: INVESTIGATION OF SOME KEY OPERATIONAL PARAMETERS

Korean Journal of Chemical Engineering

Adsorption of Cr (VI) on synthetic hematite (α-Fe2O3) nanoparticles of different morphologies

Adsorptive removal of carbamazepine using biosynthesized hematite nanoparticles

Journal	Data powered by TypesetEnvironmental Nanotechnology, Monitoring & Management
Publisher	Data powered by TypesetElsevier BV
ISSN	2215-1532
Open Access	0