This study covers a numerical investigation of gyrotactic microorganisms contained MHD flow over a vertical plate bearing thermal radiation, thermophoresis, Brownian motion, chemical reaction and inclined magnetic field effects. With the assistance of similarity transforms, the derived governed equations are transformed as set of ODEs and solved numerically by R-K and Newton’s methods. Graphs are exhibited and explained for various parameters of interest. For engineering interest, we mainly talked about the Skin friction coefficient, reduced Sherwood, Nusselt numbers and density of motile microorganisms. We noticed a rise in the heat transfer rate of motile microorganisms for rising values of the thermophoresis and Brownian motion parameters. Increasing values of the aligned angle hikes the drag force.