The distribution network carries electricity from the transmission system and delivers it to consumers. Distribution losses account for major part of power system losses. The low-voltage operation in the distribution system is a major reason for higher technical losses due to inherent properties of the network. In this paper, a method based on invasive weed optimization algorithm (IWOA) is proposed for distribution network reconfiguration with the objective of real power loss minimization. The feeder reconfiguration problem is formulated as a nonlinear optimization problem, and IWOA is used to find the optimal solution. The proposed method is implemented on standard 16-bus test system . Test results show that the proposed feeder reconfiguration method can effectively ensure the loss minimization. © Springer India 2015.