Data mining is the concept of discovering facts from information. Data mining can mine knowledge and patterns from vast quantity of data. Mining is also considered as Knowledge mining, pattern investigation, data searching and of various forms. It is a way of examining easily and processing of query. It gathers data from numerous resources and forms a meaningful datasets. Many computing tools focus on systematic approach of data mining and permit the researchers for examining the scope, outlooks and recognized connection with the real world. This paper focuses on the challenges using Multivariate Datasets and the usage of its data in medical domain. © 2013 IEEE.