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An insight into the lipid abnormalities in type 2 diabetes mellitus patients in Vellore region, South India
Hari S.A., Asokan P.,
Published in IJPPS
Volume: 6
Issue: SUPPL. 2
Pages: 847 - 850
Objective: The objective of the present study is to evaluate the pattern of lipid profile parameters and correlate with HbA1C in Type 2 diabetes mellitus (T2DM) subjects of Vellore region, South India. Methods: 286 clinically diagnosed Type 2 diabetic patients were included for this study. Fasting blood samples were collected for HbA1C, blood glucose and lipid profile estimation. Results: Only 139 of the total patients studied (n=286) had good glycemic control (HbA1C values < 7%, Group A) and the remaining 147 had HbA1C values > 7% (Group B), indicating relatively poor glycemic control. The total cholesterol, triglycerides and non-HDL values (mg/dl) for group A were 174.3 ± 28.7, 165.9 ± 67.9 and 135.5 ± 29.3 and for group B, they were 189 ± 44.6, 203 ± 93.4 and 145.2 ± 45.4. Conclusions: The values of both the groups were above the target values recommended by the NCEP-ATPIII guidelines. The correlation of HbA1C with triglycerides was found to be more significant than correlation with other lipid parameters. Patients with good glycemic control exhibited more favorable (20.1%) blood lipid levels (none out of target) than those with poor glycemic control (6.1%). This data indicate that HbA1C can be used as a biomarker for establishing mixed dyslipidemia in T2DM. Our study indicates substantial underachievement of treatment goals by diabetic patients in both the groups.
About the journal
JournalInternational Journal of Pharmacy and Pharmaceutical Sciences
Open AccessNo