Abrasive Water Jet Machining is one of the novel nontraditional cutting processes found diverse applications in machining different kinds of difficult-to-machine materials. Process parameters play an important role in finding the economics of machining process at good quality. This research focused on the predictive models for explaining the functional relationship between input and output parameters of AWJ machining process. No single set of parametric combination of machining variables can suggest the better responses concurrently, due to its conflicting nature. Hence, an approach of Multi-objective has been attempted for the best combination of process parameters by modelling AWJM process using of ANN. It served a set of optimal process parameters to AWJ machining process, which shows a development with an enhanced productivity. Wide set of trail experiments have been considered with a broader range of machining parameters for modelling and, then, for validating. The model is capable of predicting optimized responses. © 2018 Growing Science Ltd. All rights reserved.