In this work, we consider a nonlinear resolvent integro-differential evolution inclusions in Hilbert spaces. This paper deals with the approximate controllability for nonlinear resolvent integro-differential inclusions in Hilbert spaces. We use Bohnenblust–Karlin's fixed-point theorem to establish a set of sufficient conditions for the approximate controllability for nonlinear resolvent integro-differential inclusions in Hilbert spaces. Further, we extend the result to study the approximate controllability concept with non-local conditions. An example is presented to demonstrate the obtained theory. © 2017 Informa UK Limited, trading as Taylor & Francis Group.