A high yielding green protocol is described for the synthesis of 3,2 and 3,3-diheteroaromatic oxindole involving the condensation of isatin with indole or pyrrole in an aqueous medium under neutral conditions by supramoleculer catalysis by β-cyclodextrin. The β-cyclodextrin can be easily recovered and reused without any loss of activity.

Priyankar Paira

Department of Chemistry

School of Advanced Sciences

Vellore Campus

S. Naskar

P. Saha

R. Paira

A. Hazra

K.B. Sahu

S. Banerjee

N.B. Mondal

Vellore Institute of Technology (VIT) is a private university located in&nbsp;Tamil Nadu, India. Founded in 1984, as Vellore Engineering College, the institution offers 20 undergraduate, 34 postgraduate, four integrated and four research programs. It has campuses in Vellore, Amravati, Bhopal and Chennai.

VIT is one of the top ranked private universities in India according to NIRF, THE and QS Rankings.&nbsp;Govt. of India has recognized&nbsp;VIT, Vellore as an&nbsp;Institution of Eminence. This has allowed VIT to take independent quality initiatives and move up in world ranking.

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VIT University

Aqueous phase supramoleculer synthesis of 3,2- and 3,3-dihetero-aromatic oxindoles catalysed by β-cyclodextrin

Journal of Chemical Research