In industrial applications of wireless technologies, very common, wireless sensor and actuator nodes are installed at fields. Therefore, it is critical to extend battery’s lifetime for ensuring continuous servicing period of field instruments over years. Apart from periodic battery status update during operations of the nodes, at planning stage, plant management team can estimate batteries’ lifetime at field wireless instruments for operational budget estimation and preventive maintenance planning. This work proposes a framework to estimate the battery’s lifetime taken into consideration of periodic update periods and devices’ operational frequencies. The framework is based on the knowledge of wireless node, microcontroller’s power consumption, and battery specifications. Based on the analysis, at particular operational conditions (i.e., update period of 512 s, low-power mode with voltage of 1.8 V), the estimated battery’s lifetime of a wireless node can reach up to 9 years. © 2020, King Fahd University of Petroleum & Minerals.