The eco-friendly synthesis of nanoparticles through green route from plant extracts have renowned a wide range of application in the field of modern science, due to increased drug efficacy and less toxicity in the nanosized mediated drug delivery model. In the present study, our research groups have biosynthesized the stable and cost effective copper oxide nanoparticles (CuO NPs) from the leaves of (Ormocarpum cochinchinense) O. cochinchinense. The synthesis of crystalline CuO NPs from the leaf extract of O. cochinchinense were confirmed by various analytical techniques like UV-Visible Spectroscopy (UV-Vis), Fourier-Transform Infrared Spectroscopy (FT-IR), X-Ray Diffractometer (XRD), Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM) and Selected Area Electron Diffraction (SAED) pattern. Further the synthesized CuO NPs were screened for anticancer activity on human colon cancer cell lines (HCT-116) by MTT (3-(4,5-dimethyl-2-tiazolyl)-2,5-diphenyl-2-tetrazolium bromide) assay. The obtained result inferred that the synthesized CuO NPs demonstrated high anticancer cytotoxicity on human colon cancer cell lines (HCT-116) with IC50 value of 40μgmL-1 were discussed briefly in this manuscript.

Mohana Roopan S

Department of Chemistry

School of Advanced Sciences

Vellore Campus

Gnanavel V

Palanichamy V

Vellore Institute of Technology (VIT) is a private university located in&nbsp;Tamil Nadu, India. Founded in 1984, as Vellore Engineering College, the institution offers 20 undergraduate, 34 postgraduate, four integrated and four research programs. It has campuses in Vellore, Amravati, Bhopal and Chennai.

VIT is one of the top ranked private universities in India according to NIRF, THE and QS Rankings.&nbsp;Govt. of India has recognized&nbsp;VIT, Vellore as an&nbsp;Institution of Eminence. This has allowed VIT to take independent quality initiatives and move up in world ranking.

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VIT University

Journal of Photochemistry and Photobiology B: Biology

The aim of the present study was actinomycetes mediated biosynthesis of copper oxide nanoparticles (CuO NPs) and evaluation of its antibacterial activity against selected human and fish pathogens. The biosynthesized CuO NPs were characterized by UV–Visible (UV-Vis) spectroscopy. The presence of capping agents over the metal nanoparticles was confirmed by Fourier-Transform Infrared Spectroscopy (FT-IR). The crystalline nature of the CuO NPs was illustrated by X- Ray diffractometer (XRD). The average size of the biosynthesized CuO NPs from XRD and Transmission Electron Microscopy (TEM) was 61.7 nm. The XRD and Energy Dispersive X-Ray spectroscopy (EDX) suggests the purity of the biosynthesized CuO NPs. The morphology and size was viewed under Scanning Electron Microscopy (SEM). The Dynamic Light Scattering (DLS) results provided the zeta potential of − 31.1 mV which further confirmed the stability of the CuO NPs. The biosynthesized CuO NPs showed higher antibacterial activity (zone of inhibition) against various human and fish bacterial pathogens (Staphylococcus aureus, Bacillus cereus, Proteus mirabilis, Edwardsiella tarda, Aeromonas caviae, Aeromonas hydrophila and Vibrio anguillarum). The antibacterial activity of CuO NPs was significantly higher than the activity exhibited by cell free supernatant of actinomycetes. Among the pathogens tested B. cereus was more susceptible (25.3 mm) to biosynthesized CuO NPs. The antibacterial activity exhibited by the actinomycetes mediated biosynthesized CuO NPs suggests that it can combat both human as well as fish bacterial pathogens. To the best of our knowledge, this is the first report on actinomycetes mediated biosynthesis of CuO NPs. © 2018 Elsevier Ltd

Biocatalysis and Agricultural Biotechnology

Biosynthesis, characterization and antibacterial activity of copper oxide nanoparticles (CuO NPs) from actinomycetes

Ecofriendly synthesis of Palladium nanoparticles (PdNPs) were achieved using Phyllanthus emblica (P. emblica) seeds as reducing agent. Further the ecofriendly synthesized PdNPs were subjected for various analytical techniques like UV–Vis, FT-IR, XRD, Zeta potential, SEM and TEM. The results indicated that green synthesized PdNPs were spherical in shape with average particle size of 28 ± 2 nm with moderate stability. Further the synthesized PdNPs and extract were subjected for its antibacterial studies against various disease causing pathogens by agar well diffusion method. Seed extract resulted in 8.9 ± 1.46 mm against B. subtilis and PdNPs showed 9.6 ± 1.10 mm against S. aureus and synthesized PdNPs and extract were tested for hemolytic which resulted in 20% and 10% respectively. Toxicity studies were done against Artemia salina (A. salina). The LC50 value of green synthesized P. emblica capped PdNPs and the P. emblica seed extract were found to be less toxic for A. salina with a value of 1.00 μg/mL and 1.25 μg/mL. In addition samples were checked for in vitro cytotoxicity assays on HeLa cell lines. © 2016 Elsevier B.V.

Phyllanthus emblica seed extract mediated synthesis of PdNPs against antibacterial, heamolytic and cytotoxic studies

In this era, researchers have mainly concentrated on green synthesis of nanoparticles which is rapid, nontoxic, ecofriendly, reproducible and less cost when compared to the chemical and physical methods. Phytochemical reduction of AgNO3 to Ag NPs using root bark extracts of Catunaregum spinosa (C. spinosa) is reported in this manuscript. The resulting bio-reduced Silver nanoparticles (Ag NPs) were analyzed by UV–Visible Spectroscopy, FT-IR, XRD, TEM, Zeta potential and EDAX. Preparation of Ag NPs was identified by transformation of color from white to brown with maximum absorption at 442 nm due to Surface Plasmon Resonance. Crystalline studies by XRD inferred that the biosynthesized Ag NPs were crystalline in nature and further morphological studies revealed that the particles were spherically agglomerated with size ranging from 33 ± 2 nm. Moreover, the green synthesized Ag NPs were subjected for the degradation of toxic Amaranth dye using photoreactor exactly at 365 nm and pseudo first order kinetics were also stated the rate of degradation reaction were identified to be − K = 0.932 which provides significant results showing 94.07% degradation of azo grouped dye. © 2016 Elsevier B.V.

Journal of Molecular Liquids

Catunaregum spinosa capped Ag NPs and its photocatalytic application against amaranth toxic azo dye

Tin oxide (SnO2) nanoparticles were prepared using Persia Americana seed methanolic extract by calcining stannous chloride precursors at 300-500 °C by green synthesis method. Synthesized SnO2 NPs were confirmed via characterization techniques such as UV-visible spectroscopy (UV), X-ray diffraction (XRD), Scanning Electron Microscope (SEM) and Energy Dispersive X-ray analysis (EDAX). The results of characterization technique states that the synthesized nanoparticles were in the size of 4 nm and further we have undergone catalytic degradation of organic dye named phenolsulfonphthalein (phenol red). The result showed that SnO2 NPs shows much degradation activity by the catalytic action of long UV exactly at 365 nm. © 2015 Elsevier B.V. All rights reserved.

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy

Green synthesis of SnO 2 nanoparticles and its photocatalytic activity of phenolsulfonphthalein dye

Cocos nucifera is one of the most adaptable products which possess several protein fractions such as albumins, globulins, prolamines, glutelins 1 and 2 which were found and reported. Since C. nucifera was rich in nutritional value, it has wide medicinal applications. In this manuscript, we have reviewed on the anti-inflammatory, antioxidant, antimicrobial, antimalarial, leishmanicidal, and insecticidal activity. Also C. nucifera act as a low cost agricultural waste which was widely used in the preparation of nanoparticles: in this review, we have also focused on silver, gold, aluminum oxide, and doped nanoparticles like europium doped yttrium oxide nanoparticles. © 2015 Elsevier B.V.

Industrial Crops and Products

Exploitation of Cocos nucifera a non-food toward the biological and nanobiotechnology field

In this paper, we have established for the first time, the terrific efficiency of aqueous extract of agricultural waste dried peel of sugar apple (Annona squamosa) in the rapid synthesis of stable SnO2 nanoparticles. In topical years, the deployment of secondary metabolites from plant extract has emerged as a novel technology for the synthesis of various nanoparticles. In this paper, we have studied the potential of SnO2 nanoparticles assembly using agricultural waste source for the first time. The synthesized nanoparticles were characterized and confirmed as SnO2 nanoparticles by using UV-visible spectroscopy, XRD, and TEM analysis. The motivation of this study was to examine cytotoxicity study of SnO2 nanoparticles against hepatocellular carcinoma cell line (HepG2). SnO2 nanoparticles inhibited the cell proliferation in a dose- and time-dependent manner with an IC50 value of 148 μg/mL. The treated cells showed an altered morphology with increasing concentrations of SnO2 nanoparticles. Our result shows that the SnO2 nanoparticles exhibit moderate cytotoxicity towards the hepatocellular carcinoma (HepG2) at tested concentrations.

Journal	Data powered by TypesetJournal of Photochemistry and Photobiology B: Biology
Publisher	Data powered by TypesetElsevier BV
ISSN	1011-1344
Open Access	0