The objective of this work was to explore an alternative way to manage the non-biodegradable and non-recyclable fraction of municipal solid waste (MSW) in Vellore city, India. Refuse-derived fuel (RDF) samples with different proportions of plastic, thermocol, foam and jute straw were formulated. The RDF samples were characterized in the form of heating values (proximate and ultimate analysis), surface properties through X-ray diffraction (XRD) and thermal stability through thermogravimetric analysis (TGA). The measured higher heating values (HHV) of four RDF samples varying between 6032 and 6168 kcal/kg were effectively modelled using various empirical models for the prediction of HHV based on their elemental analysis. Higher absolute weight loss in TGA was evident in samples with jute straw while the highest rate of weight loss was noted in samples with a higher proportion of thermocol. Results from this preliminary investigation of RDF samples prepared from non-biodegradable and non-recyclable fractions of MSW warrants an exhaustive analysis of a larger pool of samples to project appropriate RDF composition for better energy recovery. © 2020 Informa UK Limited, trading as Taylor & Francis Group.