S rej

K chanda

Cy chiu

Michael h huang

Vellore Institute of Technology (VIT) is a private university located in&nbsp;Tamil Nadu, India. Founded in 1984, as Vellore Engineering College, the institution offers 20 undergraduate, 34 postgraduate, four integrated and four research programs. It has campuses in Vellore, Amravati, Bhopal and Chennai.

VIT is one of the top ranked private universities in India according to NIRF, THE and QS Rankings.&nbsp;Govt. of India has recognized&nbsp;VIT, Vellore as an&nbsp;Institution of Eminence. This has allowed VIT to take independent quality initiatives and move up in world ranking.

&nbsp;

&nbsp;

VIT University

Chemistry - A European Journal

Simultaneous C−N, and N−N bond-forming methods for one-pot transformations are highly challenging in synthetic organic chemistry. In this study, the Cu2O rhombic dodecahedra-catalyzed synthesis of 2H-indazoles is demonstrated with good to excellent yields from readily available chemicals. This one-pot procedure involves Cu2O nanoparticle-catalyzed consecutive C−N, and N−N bond formation followed by cyclization to yield 2H-indazoles with broad substrate scope and high functional group tolerance. Various cell-based bioassay studies demonstrated that 2H-indazoles inhibit the growth of cancer cells, typically through induction of apoptosis in a dose-dependent manner. Moreover, 2H-indazoles tested in the MDA-MB-468 cell line were capable of inhibiting cancer cell migration and invasion. Thus, it is shown that 2H-indazoles have potent in vitro anticancer activity that warrant further investigation of this compound class.

Fulltext

ChemMedChem

Assembly of Fully Substituted 2H-Indazoles Catalyzed by Cu2O Rhombic Dodecahedra and Evaluation of Anticancer Activity

Nanoscale

Direct formation of small Cu2O nanocubes, octahedra, and octapods for efficient synthesis of triazoles

Journal of the American Chemical Society

Aqueous Phase Synthesis of Au–Ag Core–Shell Nanocrystals with Tunable Shapes and Their Optical and Catalytic Properties

Chemical Communications

Facet-dependent properties of polyhedral nanocrystals

Facet-dependent optical properties of polyhedral Au–Cu2O core–shell nanocrystals

Facet-Dependent Catalytic Activity of Cu2O Nanocrystals in the One-Pot Synthesis of 1,2,3-Triazoles by Multicomponent Click Reactions

Control of Regioselectivity over Gold Nanocrystals of Different Surfaces for the Synthesis of 1,4-Disubstituted Triazole through the Click Reaction

Journal	Data powered by TypesetChemistry - A European Journal
Publisher	Data powered by TypesetWiley
ISSN	0947-6539
Open Access	0