In this paper, we consider a class of fractional neutral integro-differential equations with unbounded delay in Banach spaces. This paper deals with the exact controllability for fractional integro-differential neutral control systems. First, we establish a new set of sufficient conditions for the exact controllability of nonlinear fractional systems by using a fixed point analysis approach. Further, we extend the result to study the exact controllability concept with nonlocal conditions. Examples are provided to illustrate our main results. © 2014 Elsevier Inc. All rights reserved.