Medical image data protection is very important as medical image sharing has increased tremendously. Cryptography and image steganography are two important fields that help in medical data security. The security of the medical images has always been a concern. The method proposed could be used to securely transfer the medical images over the internet. An approach is proposed to combine both concepts of steganography and cryptography together to attain various medical image security attacks. In the proposed framework, the message is embedded in the image. Blowfish algorithm is used for encryption and decryption of image. LSB algorithm is utilized to embed the message into the image. The proposed approach mainly concentrates on the confidentiality of patient information during the transfer of medical images over the internet. © 2006-2014 Asian Research Publishing Network (ARPN).