Assistive technology is a rapidly growing field in the area of science and technology and is considered to be the part and parcel of the present technological innovations. A wheelchair is the most common assistive technology used globally to imparentation of an integrated electric wheelchair with multi-interface systems to address all classes of disabilitiet personal mobility among people with disabilities. This paper describes the design and implems. The proposed system can respond to multiple inputs from the user based on the mode selected. The modes considered are speech, gesture and vision. An additional mode for autonomous navigation has also been implemented in the form of line/wall following principle. The wheelchair unit is incorporated with speech based home automation to make the users self-dependent. The integrated system aims at providing the user with multiple modes of control for mobility as well as control of appliances in the living environment. © 2006-2016 Asian Research Publishing Network (ARPN). All rights reserved.