Hemoglobin (Hb) is the most important vital parameter of red blood cells. Its level in human body is a vital analytic parameter for diagnosing chronic and acute anemic conditions. At present, invasive techniques are employed to quantify the Hemoglobin absorption, by which blood is sampled out from the patient and followed by laboratory analysis. Apart from the fear of needles or the pain, the invasive technique offers other risks disease transmission, needle contamination and time consuming process. Thus it does not allow real time patient monitoring also requires facility and clinicians. The light absorbed by both the form of hemoglobin i.e., oxygenated and deoxygenated is determined. Red and IR LED are used to illuminate and transmitted light through the finger was detected by a photodiode. The coefficient of absorption for blood varies for every different wavelength. The paper offers the design parameters and experimental design of the probe for non-invasive hemoglobin measurement device. The finger when inserted into the probe, photonsof light from the LEDs illuminate on the finger, and a Si Photo detector computes the amount of light transmitted. The probe worn around the finger has a lot of design considerations. They are the inside color, area of the photo detector, and the space between the source and detector. © Research India Publications.