The presence of velopharyngeal dysfunction in individuals with cleft palate (CP) nasalizes the voiced stops. Due to this, voiced stops (/b/, /d/, /g/) tend to be perceive like nasal consonants (/m/, /n/, /ng/). In this work, a novel algorithm is proposed for the detection of nasalized voiced stops in CP speech using epoch-synchronous features. Speech regions corresponding to consonant and consonant-vowel transitions are segmented using the knowledge of glottal activity, syllable nucleus, low-frequency spectral dominance, and vowel onset point. The segmented regions are epoch-synchronously processed to analyze the spectral, spectro-temporal, excitation source, and periodicity characteristics of normal and nasalized voiced stops. Spectral and spectro temporal features are computed using single pole filter based time-frequency representation. The amplitude of Hilbert envelope of linear prediction residual, measured around the epoch is used to analyze the effect of nasalization on excitation source. Comparison of speech frames of successive inter-epoch intervals is carried out to analyze the periodicity characteristics. The proposed features are used to develop a support vector machine classifier for the classification of normal and nasalized voiced stops. Segmentation accuracy for the proposed knowledge based method is found to be better than the hidden Markov model based force-alignment approach. The detection rate of nasalized voiced stops is found to be high for the proposed epoch synchronous features than the conventional Mel-frequency cepstral coefficients. © 2014 IEEE.