Diagnosis of fracture and treatment always pose a challenge to medical practitioners. A DC voltage in the range of 0.1 to 0.7V was applied across tibia fracture site stabilized with Teflon coated carbon rings and the data was recorded at various patient follow-up periods. Using the concept proposed in one of our earlier work, a regular pattern of variation of capacitance is observed across the tibia fracture site exhibiting capacitance. In this work we determine the optimum voltage required for the following of the fracture treatment. The electrical data was recorded across radiographs different tibia fracture patients classified into 4 group's namely fresh presentation, presentation after a medium delay, presentation after a long delay and fracture with gap. The variation of capacitance for the range of applied input voltage 0.1 to 0.7V was calibrated. The data was subjected to Analysis of Variance (ANOVA). An ANOVA analysis of the four groups indicated a significant level F ratio and P value which suggested that results are at confident interval. From the results the best optimum value for applying input voltage for the tibia fracture case is 0.1volt.