Internet of Things (IoT) is the connection with the network and physical devices, objects, vehicles, electronics, software, sensors, which are connected to the internet for collect and exchange data and connected to actuators, drones, and robots etc. The main objective of the research should be able to develop the framework for the unique format to communicate multiple devices for any format of the file and address the Security challenges of the fifth-generation mobile networks. Healthcare is an essential part of everyone's life. Modern healthcare applications require a huge demand for IoT Devices from hospital beds to doctors and this will be more advantages for the nurses and patients at the same time data from these devices need to be more secure. This solution was mainly used to decrease pressure on health applications to use this framework solution by providing the continue to quality to decrease the risk in patients. Internet of Things(IoT) used to identify a more important solution to mitigate pressure on healthcare applications. The main objective of the research should be able to develop the framework for the unique format to communicate the multiple devices for any format of the file and address the Security challenges of fifth generation mobile networks in Healthcare applications. In the Next Generation of Fifth Generation Mobile Network Communications in this communication is very different in that which we are used currently. Demand for mobile broadband and wireless communication will continue to increase, largely driven by ultrahigh definition videos with better screens, due to the tech-savvy mobile community and to propose the security algorithms. © 2018 IEEE.