Toxic organic pollutant and the products concern due to their persistency and slow A which is used for plastic production an removal process, we have isolated two I capability to remove bisphenol-A. Co-cull removal (80% removal in 72 hr) compar optimization on different parameters (bispi and NaCI concentration) was examined for that affects bioremoval was identified a design with the positive effect. Study on method showed glucose as carbon sour The co-cultured system thus exhibited source and this potential could be inves water with multiple endocrine disruptors manufactured out of it are becoming an increasing r degradation rate. One such compound is bisphenolcauses endocrine disruption. To develop a biological acterial strains (VIT-Pi and VIT-Wi) which have a iring of these two isolated strains showed a higher d to individual strain's removal efficiency. Classical enol-A concentration, time, pH, glucose concentration he co-culture system. The most significant parameter bisphenol-A concentration by the Plackett-Burman process optimization by both classical and statistical e demonstrated insignificant effect on bioremoval. apability to utilize bisphenol-A as the sole carbon igated to advance the treatment process for waste-water with multiple disruptors. © 2018 Kalpana Corporation.