In contrary to the existing externally powered photodetectors, a reliable approach for self-powered photodetection is designed for the first time through an internally integrated concept via coupling of piezotronic with photonic effects. A flexile self-powered photodetector (F-SPPD) developed by one-dimensionally grown floral-like F-ZnO nanorods on a poly(vinylidene difluoride) substrate conjointly performs the tunability of optical properties through the exploitation of strain-induced piezoelectric potentials (σ+, σ-) at the electrode interfaces. The experimental observation showed an ideal photodetector characteristics with a 1-fold increment in photoresponsivity (R365nm ∼ 22.76 mA/W) by lowered Schottky barrier heights (φSB1T, φSB2T) through externally governed tensile strain (+ϵ). Further, the self-powered operation mode of F-SPPD exhibited higher spectral sensitivity (5.69 mA/(W cm-2)) than that of the photodetector (3.47 mA/(W cm-2)) operated under unstrained condition. This work effectively brings in the direct integration ideology of two different systems into a single module toward the downscaling of device size and weight. © 2018 American Chemical Society.