Laser beam welding of commercially pure titanium sheets were carried out at different operating conditions. Laser powers of 2.0 and 2.5 kW, beam diameters of 0.18 and 0.36 mm and welding speeds of 4–8 m/min were used. The microstructure and mechanical properties of the welded samples were investigated in the present study. It was observed that the grain size of the welded samples increased with increasing laser power while it decreased with increasing welding speed and beam diameter. The sample welded at 2.5 kW laser power with 4 m/min welding speed and 0.36 mm beam diameter had comparable tensile properties with the base metal. © 2016, The Indian Institute of Metals - IIM.