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Efficacy of herbal drugs in treatment of galactosamine-induced hepatotoxicity in rats
P.S. Gaopande, P.S. Jerine, , S.E. Prince
Published in World Research Association
2021
Volume: 16
   
Issue: 5
Pages: 239 - 246
Abstract
Liver plays an important role in drug metabolism. Presence of any toxic compound in drug or formation of toxic metabolites during hepatic metabolism of drug may cause hepatotoxicity. Galactosamine is the experimental drug which causes hepatotoxicity by two basic mechanisms i.e. inflammation and peroxidation. Natural compounds which are derived from trees or herbs have anti-inflammatory and antioxidant properties which are efficient to prevent or cure the drug- induced hepatotoxicity. These herbal compounds are easily available in nature and also their extraction procedures are less expensive. Moreover, herbal drugs have negligible side -effects as compared to the synthetic drugs available in the market. This review mainly focuses on the different measures of Galactosamine-induced hepatotoxicity and also the herbal drugs which can be employed to cure Galactosamine-induced hepatotoxicity. © 2021 World Research Association. All rights reserved.
About the journal
JournalResearch Journal of Biotechnology
PublisherWorld Research Association
ISSN09736263