Ramipril, an angiotensin converting enzyme inhibitor, has a relatively low bioavailability due to its poor aqueous insolubility. Microemulsion system composed of clove oil, tween 20 and water (5:30:65 v/v) was investigated as a potential drug delivery system to enhance the water solubility and stability of the drug through simple emulsion concept. Electrical conductivity was done to confirm whether the microemulsion system formed is oilcontinuous or water-continuous. Extreme stress conditions were performed to delineate the microemulsions. Centrifugation test confirmed the physical stability of the microemulsion. Further, pH and viscosity measurements were carried out in characterizing the optimized formulation. The optically clear and low-viscous formulation with enhanced solubility and stability has a significant promise in increasing the effectiveness of very sparingly soluble drug.