Objectives: Our study focused on improving or enhancing the solubilization effect of many water insoluble drugs that are under the category BCS Class II-IV. Methods: The solubility of ten such drugs was checked in clove and cinnamon oils, owing to their higher solubility capacity. Results: Out of these drugs, carvedilol, followed by, ezetimibe and olmesartan showed good solubilization in both these oils. Conclusion: These oils could thus be used in the development of drug delivery system for the above-mentioned drugs.