The evacuated tube collector with U shape copper absorber tube is considered for the analysis. The experimental investigation is conducted on parabolic trough collector with U shape tube as absorber tube. The effect of the sudden fluctuations in the solar radiation on the performance of the collector is reduced by means of evacuated tube collector filled with thermic fluids. The analysis is performed with different thermic fluids such as dowtherm, therminol66, glycol water and ethylene glycol, are filled in the annular space between inner glass tube and U shape copper absorber tube. The experimentation is carried out at various mass flow rates from 20 to 100 LPH with the step-up flow rate of 20 LPH. A comparative study is carried out on various parameters such as effect of mass flow rate over instantaneous efficiency, useful heat gain and work input, etc. The characteristic curve of cylindrical parabolic trough collector (PTC) is also discussed. Experimental results show that, ethylene glycol gives better efficiency over mass flow rate and therminol66 gives best power heat ratio. Heat transfer mediums and its properties [specific heat capacity, thermal conductivity and dynamic viscosity] for all specified heat transfer fluids are also discussed. The results obtained with various specified heat transfer fluids filled in the annulus space of evacuated tube are compared with plain evacuated tube. It is observed that there is significant enhancement of overall instantaneous collection efficiency of the parabolic trough collector. © 2018, Allerton Press, Inc.