This paper reports on an exploratory research work carried out aiming to identify the barriers in the usage of traditional medicines by the holders of the knowledge. The focus is on the usage of the traditional medicines by the homogenous people, Malayali tribe community at Shervaroy hills of Eastern Ghats. Semi-structured interviews were conducted among the tribe community of the area. Where the knowledge has been passed on from generations making the traditional medicinal knowledge strongly imbibed in their culture, the research findings divulged the reasons as to why in spite of having immense knowledge on traditional medicines these tribe community are opting for codified from of medicines. This report also explored the understanding of older generation in the context of holders of the traditional medicinal knowledge among the Malayali tribe community. The conclusion supports the implementation of existing policies stringently with recommendations so as to draw closer towards the three objectives enshrined in the Convention of Biodiversity and Biological Diversity Act, 2002. This paper contributes to the policy makers, pharmaceutical companies, non-governmental organizations and the holders of traditional medicinal knowledge so as to collaborate, in the process, protecting and promoting the traditional knowledge in medicinal plants.