Test case generation is among the most labour-intensive tasks in software testing. It has a strong impact on the effectiveness and efficiency of software testing. For these reasons, it has also been one of the most active topics in the research on software testing for several decades, resulting in many different approaches and tools. We present a comprehensive test case generation technique from UML models. We use the features in UML 2.0 use case diagram including conditions, iterations, asynchronous messages and concurrent components. In our approach, test cases are derived from analysis artifacts such as use cases and constraints specified across all these artifacts. We construct Use case Dependency Graph (UDG) from use case diagram. The test cases thus generated are suitable for detecting synchronization and dependency of use cases and messages, object interaction and operational faults. © Research India Publications.