Purpose: The purpose of this paper is to provide an insight into the influence of gyrotactic microorganisms and Hall effect on the boundary layer flow of 29 nm CuO-water mixture on the upper pointed surface of a rocket, over the bonnet of a car and upper pointed surface of an aircraft. This is true since all these objects are examples of an object with variable thickness. Design/methodology/approach: The simplification of Rosseland approximation (Taylor series expansion of T4 about T∞) is avoided; thus, two different parameters relating to the study of nonlinear thermal radiation are obtained. The governing equation is non-dimensionalized, parameterized and solved numerically. Findings: Maximum vertical and horizontal velocities of the 29 nm CuO-water nanofluid flow is guaranteed at a small value of Peclet number and large value of buoyancy parameter depending on the temperature difference. When the magnitude of thickness parameter χ is small, cross-flow velocity decreases with the velocity index and the opposite effect is observed when the magnitude of χ is large. Originality/value: Directly or indirectly, the importance of the fluid flow which contains 29 nm CuO nanoparticle, water, and gyrotactic microorganisms in the presence of Hall current has been pointed out as an open question in the literature due to its relevance in imaging, ophthalmological and translational medicine informatics. © 2018, Emerald Publishing Limited.