In this paper, a novel fusion scheme based on 2D-discrete fractional Fourier transform (2D-DFRFT) is proposed. In the proposed scheme, input source images are transformed using 2D-DFRFT and then subtracted from the respective source images to obtained the detail images. The detail images are further used to generate the fused image using appropriate fusion rule. The additional degree of freedom in terms of its angle parameters associated with the 2D-DFRFT is exploited for obtaining better results in the proposed fusion scheme. Performance evaluation of fused images is done by computing fusion quality metrics and the fusion results are compared with other existing fusion schemes. It is seen that the performance of the proposed scheme is better in terms of the fusion quality metrics as compared to the existing fusion schemes. © 2017 IEEE.