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Induction of oxalate binding by dehydroascorbic acid feeding in rat kidney
R. Selvam,
Published in
1993
Volume: 13
   
Issue: 6
Pages: 667 - 676
Abstract
Feeding dehydroascorbic acid (DHA) to rats produced hyperoxaluria, hypercalcuria and increased retention of oxalate in kidney. Increased oxalate binding in kidney was observed in DHA fed rats and it was found to be associated with increased lipid peroxidation (LPO) reaction and decreased activity of antioxidant enzymes superoxide dismutase (SOD), glutathione peroxidase (GPX), catalase and glutathione-s-transferase (GST) and decreased levels of oxygen free radical scavengers glutathione (GSH) and vitamin E. © 1993 Pergamon Press Ltd.
About the journal
JournalNutrition Research
ISSN02715317