AbstractPresent analysis is to study the combined effects of viscous dissipation and Joule heating on MHD three-dimensional laminar flow of a viscous incompressible non-linear radiating Casson nanofluid past a nonlinear stretching porous sheet. Present model describes that flow generated by bi-directional non-linear stretching sheet with thermophoresis and Brownian motion effects. The governing nonlinear partial differential equations are transformed into a system of nonlinear coupled ordinary differential equations by similarity transformations and then solved by employing shooting method. The effects of the flow parameters on the velocity, temperature and concentration as well as the skin friction coefficient, Nusselt number and Sherwood number near the wall are computed for various values of the fluid properties. This study reveals that the temperature of Casson nanofluid increases with combination of viscous dissipation and Joule heating. Increasing thermophoresis parameter increases the species concentration of the nanoflow. The comparison of present results have been made with the published work and the results are found to be very good agreement.