The combined effects of thermal and mechanical loadings on the distribution of interlaminar shear stresses in composite laminated thin and moderately thick composite plates are investigated numerically using the commercially available software package MSC NASTRAN/PATRAN. The validity of the present finite element analysis is demonstrated by comparing the interlaminar shear stresses evaluated using the experimental measurement. Various parametric studies are also performed to investigate the effect of stacking sequences, length to thickness ratio, and boundary conditions on the interlaminar shear stresses with identical mechanical and thermal loadings. It is observed that the effect of thermal environment on the interlaminar shear stresses in carbon-epoxy fiber-reinforced composite laminated plates are much higher in asymmetric cross-ply laminate and anti-symmetric laminate compared to symmetric cross-ply laminate and unidirectional laminate under identical loadings and boundary conditions. © 2016 Taylor and Francis Group, LLC.