Background and Objective: The Internet of Things (IoT) has intended for enabling the physical devices to connect over the internet, that's able to exchange the data between the physical devices in heterogeneous wireless sensor network environment. IoT paradigm is the integration of several technologies such as wireless sensor, actuator networks, identification and tracking technologies, distributed intelligence, enhanced a communication protocol which provides the communication solution among the objects. Materials and Methods: The combination of the emerging technologies and Internet transform physical objects into smart objects, able to learn, understand and react to their environment by itself. In coming years, IoT is expected to introduce the new technologies and applications for connection between the physical objects and intelligent decision-making. Conclusion: This paper presents the detailed summary of the Internet of Things introduction, visions, enabling technologies, Architectural details, protocols and its standard specification, research opportunities and challenges and application related issues. © 2016, International Journal of Pharmacy and Technology. All rights reserved.