Isolation of β-glucan from Eleusine coracana and its antibiofilm, antidiabetic, antioxidant, and biocompatible activities

Divya M; Ravi C; Govindarajan P; Alharbi N.S; Kadaikunnan S; Khaled J.M; Almanaa T.N; Vaseeharan B.; Karthikeyan S

doi:10.1016/j.micpath.2019.103955

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Journal Article

Isolation of β-glucan from Eleusine coracana and its antibiofilm, antidiabetic, antioxidant, and biocompatible activities

Divya M, Ravi C, , Alharbi N.S, Kadaikunnan S, Khaled J.M, Almanaa T.N, Vaseeharan B.,

Published in Elsevier BV

2020

DOI: 10.1016/j.micpath.2019.103955

PMID: 31899325

Volume: 140

Abstract

Eleusine coracana (Finger millet) has high nutritional value with numerous health benefits and is of low cost. Isolation of beta-glucan (βG) from E. coracana (Ec-βG) has gained increasing research attention. UV-vis spectroscopy used to measure the surface plasmon resonance at 361 nm to confirm the presence of polysaccharides (glucan molecules) in Ec-βG. X-ray diffraction analysis of Ec-βG displayed a crystalline nature and confirmed the presence of the βG molecule. Further, the bioactive compounds of Ec-βG were screened using gas chromatography-mass spectrometry. The antibacterial activity of Ec-βG against both Gram-positive (Lysinibacillus fusiformis, Enterococcus faecalis) and Gram-negative (Proteus vulgaris, Shigella sonnei) bacteria were assessed through minimum inhibitory concentrations

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