CRM focus on managing the relationship between a company and its current and prospective customer base as a key to success. A good relationship with the customer leads to higher customer satisfaction. Despite its importance the failure rate is higher because of the Implementation and integration problems. We are trying to address this issue by developing the CRM system using GME through meta-model approach. GME is a configurable toolset that supports the easy creation of domain specific modeling and program synthesis environment. Enterprises of all descriptions have long sought to integrate and manage all of their information assets within a single system. The goal remains elusive as enterprises create and store their assets in a myriad of disparate systems such as relational databases. In this paper we outline the integration Issues and describe the concepts MOF and GME and how they can be used for developing the CRM system that provides seamless integration among the components within the system and also its integration with other applications. © 2007 IEEE.