Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental pollutants generated from both natural and anthropogenic processes. They are found in various matrices such as air, water, soil and also in processed food products (highly cooked meats) and are mainly classified based on their molecular weight into two groups, Low Molecular Weight (LMW) and High Molecular Weight (HMW) compounds. Out of these two, HMW PAHs are known to be persistent for longer periods and found to show mutagenic and carcinogenic effect in many organisms. Bioremediation is an effective and safe method compared to many other processes. Various researchers have studied and reported on bioremediation of PAH compounds by bacteria, algae, fungi, yeasts and plants till date. The remediation organisms are found to convert into highly toxic PAH compounds to less harmful compounds. Microbial consortium degradation studies on inter-generic and inter-species microorganisms on PAH degradation has shown to improve the degradation rate when compared with individual organisms. Major enzymes involved in the bioremediation are manganese peroxidase (MnP), lignin peroxidise, laccaseetc. This review paper focuses on the degradation of HMW PAHs by different microorganisms.