Header menu link for other important links
X
Microwave-Assisted Synthesis of Positional Isomeric Dihydro-triazolo-pyrimido-acridines and Biological studies
R. Sompalle, , D.D. Priya, , G. Sarkar, M. Ranjith, M. Arunachalapandi
Published in Wiley-Blackwell
2020
Volume: 5
   
Issue: 10
Pages: 3085 - 3090
Abstract

Microwave synthetic methodologies were proposed for the preparation of positional isomeric dihydro-triazolo-pyrimido-acridines, 3 a-j and 9 a-h via friedlander synthesis using response surface methodology (RSM). The advantages of these methodologies over conventional methods are it provides good yields with short reaction times. Free radical scavenging and antifungal studies were performed for compounds 3 a-j and 9 a-h. The results of antioxidant assay revealed that compounds 3 c, 3 d and 9 b exhibited excellent property whereas compounds 3 a and 9 a showed significant antifungal property against Aspergillus flavus (A.flavus) and Aspergillus niger (A. niger). © 2020 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim

About the journal
JournalData powered by TypesetChemistrySelect
PublisherData powered by TypesetWiley-Blackwell
ISSN23656549